Michael Zhang

Michael Zhang

Dr. Zhang's backgrounds include medicine with an MD and Master of clinical oncology from Peking University Health Science Center and environmental toxicology with a PhD from University of California, Riverside. Work experience ranges from practicing general surgery, new drug development and submission in phases from pre-clinical development to clinical trials, construction of physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) models, and human exposure/risk assessment for environmental toxicants. Currently working as a research scientist, Dr. Zhang's research interests include clinical outcome studies using large databases to improve clinical practice and healthcare use, and surgical procedures and devices to improve treatment.

Selected Publications      

  • Zhang X, He L, Lu Y, Liu M, Huang X. Androgen receptor in primary hepatocellular carcinoma and its clinical significance. Chin Med J (Engl) 1998;111(12):1083-6.
  • Zhang X, Tsang AM, Okino MS, Power FW, Knaak JB, Harrison LS, and Dary CC. A Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Carbofuran in Sprague-Dawley Rats Using the Exposure Related Dose Estimating Model. Toxicol Sci 2007;100(2),345-59.
  • Zhang X, Driver JH, Li YH, Ross JH, Krieger RI. Dialkylphosphates (DAPs) in fruits and vegetables may confound biomonitoring in organophosphorus insecticide exposure and risk assessment. J Agric Food Chem 2008;56 (22):10638-645.
  • Zhang X, Acevedo S, Chao Y, Chen Z, Dinoff T, Driver J, Ross J, Williams R, Krieger R. Concurrent 2,4-D and triclopyr biomonitoring of backpack applicators, mixer/loader and field supervisor in forestry. Journal of Environmental Science and Health Part B Pesticides Food Contaminants and Agricultural Wastes 2011; 46(4):281-93.

Book Chapter

  • Zhang X, Knaak JB, Tornero-Velez R,Blancato JN, Dary CC. Application of physiologically based pharmacokinetic/pharmacodynamic modeling in cumulative risk assessment for N-methyl carbamate insecticides. In Handbook of Pesticide Toxicology 3rd edition, Robert Krieger. Elsevier, 2010; Chapter 73:1591-605.